Find a Business Location

The Department of Economic Development (DED) provides no cost business location services, including access to the CoStar commercial property database.  Whether you are looking for an office, lab, retail, or industrial space, DED is here to jump start your search. Connect with us to find your ideal location.

Retail Space  - 181 Thomas Johnson Drive - TJ Center

3,979 SF of Retail Space available along "Doctor's Row". Anchor tenant is Weis Grocery Store. Other tenants are Chicken Basket, Rehab at Work, Super Cuts and V&A Nails. Forty-five surface parking spaces available. Close to US 15 & I70/I270 access as well as Frederick Community College and Fort Detrick.

Contact Nancy Green with MackIntosh Realtors at 301-748-3321 for more information.

181 TJ Drive  TJ Center

Office Space - 329 East 2nd Street

Downtown office, 475 SF, with reception plus additional office; restroom, Rent includes water/sewer/electricity/Heat/AC. Separate entrance and address from Exotic Lumber. Street parking.

For more information contact Neil Gager at 410-533-2151

Office Interior   329 E. 2nd Street

889 Butterfly Lane - Prospect Hall Mansion

For Sale. 16,000 SF of available space. Located at the intersection of Butterfly Lane and Jefferson Pike (Route 180) in Frederick, with close proximity to the Golden Mile, Historic Downtown Frederick, Jefferson Tech Park, and much more. Easy access to interstates I70 and I270, and US 15. 

Potential uses: Restaurant, antique/gift shop, cultural center, office space, school, assisted living, day care, Bed & Breakfast.....

For information, contact Joe Lomangino at 410-266-5100, x128 or at

Prospect Hall renovated

Available City-Owned Properties

  • Monocacy Boulevard - (32 Acre Lot on Monocacy Boulevard) - The Monocacy Boulevard property is an excellent 32 +/- acre site ready for redevelopment. Located adjacent to the upcoming Laniary Park development and across the street from a 30 +/- acre mixed-use site currently in development, this unique property offers abundant growth opportunities.
  • Hayward Road Farmhouse - The Hayward property provides a highly visible location excellent for redevelopment. Given its light industrial zoning with an institutional overlay, this property offers abundant commercial opportunities.  The City of Frederick will be installing a water tower and salt storage facility for part of this lot, leaving approximately 0.6 acres for private for sale.
  • City of Frederick Property Disposition Policies

Additional Business Location Resources

COF Street Map 800x533